Postmortem diagnostic imaging is still underutilized, mainly due to the unawareness of its potential but also to the cost and the limited access to newer imaging modalities. Even the introduction of multidetector row helical CT scanning with isotropic 3D data acquisition and post-processing did not significantly increase the interest of pathologist in imaging. In contrast, CT has been used for paleoimaging over many years in examining mummies. Postmortem MRI was introduced for detection of gross cranial, thoracic and abdominal pathology by a few groups. Postmortem, the resolution of clinical scanners may not be sufficient to answer all relevant questions of pathology, which favors the idea of using microimaging methods with their much higher resolution and combining non-invasive imaging with minimally invasive image-guided tissue sampling from any body location. Micro-imaging of samples will add a new dimension to histopathology or even realize image guided virtual histology.
To familiarize radiologists with the application and advantages of postmortem CT, MRI, MR-Microscopy and micro-CT. Autopsy, nowadays often rejected by family members or not tolerated by religion in a multicultural society, maybe replaced by non-invasive imaging and, when required, minimally invasive image-guided tissue sampling from any body location.
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